Ahmedabad is the largest inland industrial centre in western India and has served as an important base of commerce, trade and industry.

Ahmedabad has claim to fame came for being home to the first Indian textile mill known as the Ahmedabad Spinning and Weaving Company Limited. A series of textile mills including the Calico Mills in 1880 and many such textile mills are part of its legendary status. Arvind Mills, one of India's leading composite manufacturers of textiles is headquartered in Ahmedabad.

Chemicals and pharmaceuticals industry also thrives in Ahmedabad. Americos Industries, specializing in production and marketing of high quality products like enzymes, garment wash, auxiliaries, smart colourants and dyestuffs has its headquarter in Ahmedabad.

Zydus Cadila and Torrent Pharmaceuticals, leading pharmaceutical companies in India have their headquarters here. Paras Pharmaceuticals, a reputed health and personal care company that manufactures products for day-to-day health and hygiene has its manufacturing plants located near Ahmedabad.

The city serves as the corporate headquarters of the Adani Group, which is a leading multinational trading company with revenues of $3.5 billion. The Adani group's core business includes commodities trading, edible oil manufacturing, industrial construction, Mundra port operations and distribution of natural gas.

The corporate headquarters of the Nirma group of industries which manufactures products ranging from cosmetics, soaps, detergents and salt and runs a large number of detergent and chemical industrial units is in Ahmedabad.

In the recent times, IT and IT-enabled services (ITES) and Business Process Outsourcing (BPO) companies have preferred to set up and run their offices here.More than 40 companies, including Microsoft and Tata Consultancy Services (TCS), which is part of Asia's largest conglomerates and most respected groups, are already present at Creative Infocity.

Some foreign companies have set up their sales offices and production facilities in Ahmedabad. Prominent among them are Bosch Rexroth; Germany, Stork, Rollepaal and Johnson Pumps. In the power sector, Torrent Power Limited, a part of Torrent Group is an integrated electricity generation, transmission and distribution utility. It is the sole distributor of electricity to cities of Ahmedabad, Gandhinagar and Surat.

Ahmedabad has two local FM stations. Satellite radio was launched in the city by WorldSpace in 2005. A network of optical fibre cables connects the entire city. The city's telephone service providers are landline and mobile operators like BSNL, Reliance Infocomm, Airtel, Hutch and Tata Indicom. The Gujarat film and television industry is also coming up.

Investment opportunities and real estate growth have encouraged any banks and Housing Finance Companies (HFCs) to start operating from Ahmedabad. Bank of Baroda established its first branch in Ahmedabad. The Cosmos Co-operative Bank Ltd (Cosmos Bank) one of the oldest .Urban Co-operative Bank in the India which offers core banking solutions has a branch in the city.